Abstract:
Primary vaginal cancer in women with utero vaginal prolapse is an uncommon entity. We report two women with
longstanding third degree prolapse presented with ulcerated lesions. Both had vaginal hysterectomy and anterior
colporrhaphy. Histology revealed moderately differentiated squamous cell carcinoma. One woman developed advanced
malignancy in three months of surgery and the other is surviving after five years. The latter developed a lesion in the
vagina recently and biopsy revealed poorly differentiated squamous cell carcinoma. Review of the literature and personal
experience suggest that vaginal hysterectomy and repair should be offered to women developing utero vaginal prolapse
as when longstanding chances of developing cancer of vagina becomes significant.